Cancer Therapy
Study data from Kyoto University update understanding of cancer therapy
Published in Cancer Weekly, February 10th, 2009
Data detailed in 'Telomerase-specific virotherapy in an animal model of human head and neck cancer' have been presented. According to a study from Kyoto, Japan, "Telomerase-specific replication-competent adenovirus, Telomelysin (OBP-301), has a human telomerase reverse transcriptase promoter that regulates viral replication and efficiently kills human cancer cells. The objectives of this study are to examine the effects of OBP-301 in squamous cell carcinoma of the head and neck cells in vitro and in xenografted animals in vivo."
"OBP-301 was found to be cytotoxic to the YCUT892, KCCT873, KCCT891, KCCL871, YCUM862, HN12, and KCCOR891 cell lines in vitro. However, the...
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Source: Cancer Weekly (2009-02-10)
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