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Breast Cancer

Research reports from M. Hachana and co-authors provide new insights into breast cancer

Published in Cancer Weekly, February 10th, 2009

According to recent research from Sousse, Tunisia, "Aims of the study The aim of this study was to investigate whether the Simian Virus 40 (SV40) is implicated in human breast carcinomas (BC). Experimental design SV40 presence was investigated by PCR assays targeting the Tag, the regulatory, and the VP1 regions in 109 invasive breast ductal carcinomas from Tunisian women."

"We also examined the relationship between the presence of SV40 and promoter methylation status of 15 tumor-related genes. Immunohistochemistry was used to investigate the expression of Tag, estrogen and progesterone receptors, HER2, and P53. SV40 DNA sequences were detected in 22% of tumors and in...

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