Cancer Weekly
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Cancer Gene Therapy
Study results from University of North Carolina provide new insights into cancer gene therapy
February 17th, 2009
Current study results from the report, 'In vitro and in vivo analysis of B-Myb in basal-like breast cancer,' have been published. "A defining feature of basal-like breast cancer, a breast cancer subtype with poor clinical prognosis, is the high expression of 'proliferation signature' genes. We identified B-Myb, a MYB family transcription factor that is often amplified and overexpressed in many tumor types, as being highly expressed in the proliferation signature," investigators in the United States report. "However, the roles of B-Myb in disease progression, and its mammary-specific transcriptional targets, are poorly understood. Here, we showed that B-Myb expression is...
Source: Cancer Weekly (2009-02-17)
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