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Gastrointestinal Stromal Tumors

Study data from University Medical Center update understanding of gastrointestinal stromal tumors

Published in Cancer Weekly, February 17th, 2009

In this recently published study, investigators in Hamburg, Germany conducted a study "To study the role of loss of heterozygosity (LOH) in serum microsatellite DNA of patients with gastrointestinal stromal tumors (GIST). In GIST, tumor markers from peripheral blood are missing Study: Seventy-eight patients (59 GIST. 13 leiomyomas, 2 leiomyosarcomas, and 4 schwannomas) underwent resection at our institute between 1985 and 2006."

"Thirty-three preoperative sera (26 GIST and 7 non-GIST) and 62 postoperative sera (47 GIST and I non-GIST) were available and tested for alterations in 12 representative microsatellite loci on chromosomes 22, 17, 13 9, and 3, using...

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