Glioblastoma

Data on glioblastoma published by researchers at University of Wurzburg

Published in Cancer Weekly, February 17th, 2009

"NDRG1 is a member of the N-myc downregulated gene (NDRG) family. Its induction occurs via diverse physiological and pathological conditions (hypoxia, cellular differentiation, heavy metal, N-myc, neoplasia) which modulate NDRG1 transcription, mRNA stability and translation," scientists in Wurzburg, Germany report.

"Hypoxia, among other factors, induces NDRG1 expression and plays an important role in its regulation of expression. To date, the complete detailed function of this protein in humans remains unknown. Hypoxia represents a common feature of solid tumors. In our study, differences in NDRG1 expression between different WHO grades of astrocytic tumors were...

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Source: Cancer Weekly (2009-02-17)

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