Cancer Weekly
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Adenocarcinoma
Reports from Johns Hopkins University, Medical Department describe recent advances in adenocarcinoma
February 17th, 2009
According to recent research published in the journal Modern Pathology, "Pancreatic ductal adenocarcinoma is a highly aggressive, lethal human malignancy that continues to elude successful treatment. Although most patients present with metastatic disease, the molecular pathways that underlie tumor progression and metastases are poorly understood." "The high mobility group A2 (HMGA2) protein is an architectural transcription factor that has recently been implicated in the development and progression of malignant tumors. Here, we examined HMGA2 gene expression in pancreatic ductal adenocarcinoma to determine if it could be a marker for more advanced disease. By...
Source: Cancer Weekly (2009-02-17)
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