Cancer Weekly
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Adenocarcinoma
Reports on adenocarcinoma findings from University of Padua provide new insights
February 17th, 2009
According to recent research from Padua, Italy, "Despite recent advances in surgical and multidisciplinary treatment, prognosis for patients with esophageal adenocarcinoma remains poor, and the low prognostic significance of pTNM staging suggests that additional parameters are needed. To identify genomic abnormalities characteristic of esophageal adenocarcinoma, a panel of 33 samples obtained at surgery from previously untreated patients were analyzed by muliplex ligation-dependent probe amplification technique." "We detected frequent gains of 6p, 8q, 13q, 17q, 20q, and losses of 4q, 5q, 15q, and 18q. When DNA copy number changes were correlated to clinicopathological...
Source: Cancer Weekly (2009-02-17)
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