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Cancer Weekly

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Adenocarcinoma



Research findings from R. Gupta et al update understanding of adenocarcinoma



February 17th, 2009

"Patients with advanced pulmonary adenocarcinoma exhibiting overexpression or mutation of epidermal growth factor receptor tend to respond better to targeted therapy with tyrosine kinase inhibitors such as gefitinib and erlotinib. There is no consensus regarding how these neoplasms should be routinely tested for epidermal growth factor receptor ( EGFR) and whether the results of immunohistochemistry (IHC), mutation analysis and fluorescent in situ hybridization correlate with each other or are independent predictive variables," scientists in the United States report.

"We tested 100 pulmonary adenocarcinomas from patients with stage III or IV disease for EGFR...


Source: Cancer Weekly (2009-02-17)

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