Cancer Weekly
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Angiogenesis
Study results from Y.C. Niu and colleagues broaden understanding of angiogenesis
February 17th, 2009
According to a study from People's Republic of China, "Previous studies indicated that the low molecular weight polysaccharide extracts from Agaricus blazei are potential antitumor agents or adjuvant in tumor treatment. In this study, we investigated the antitumor activity of LMPAB, a low molecular weight polysaccharide isolated from Agaricus blazei, and the molecular mechanisms of its antitumor activity." "The antitumor effect of LMPAB was examined using mouse sarcoma 180 (S 180) xenograft models. Antiangiogenic effect of LMPAB was determined by chicken embryo chorioallantoic membrane (CAM) angiogenesis and Matrigel-induced neovascularization in vivo models. The mRNA...
Source: Cancer Weekly (2009-02-17)
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