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Cancer Gene Therapy
New cancer gene therapy research from W.F. Shi and colleagues discussed
February 17th, 2009
According to a study from Shanghai, People's Republic of China, "The aim of our study was to develop an effective gene delivery system for ovarian cancer gene therapy. The expression of heparin sulfate proteoglycan (HSPG) and integrins alpha(upsilon)beta(3) and alpha(upsilon)beta(5) were analyzed with flow Cytometry on 2 human ovarian cancer cell lines (OVCAR-3 and SKOV-3ip)." "The gene transduction efficiencies were evaluated with recombinant adeno-associated viral vector (rAAV)2-green fluorescent protein or rAAV2-lactase Z followed by flow cytometry or cytohistochemistry staining. The effect of 17 beta-estradiol on ovarian cancer cell proliferation, HSPG, the...
Source: Cancer Weekly (2009-02-17)
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