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Cancer Gene Therapy

Data on cancer gene therapy described by researchers at Johns Hopkins University

Published in Cancer Weekly, February 24th, 2009

Investigators publish new data in the report 'Imaging of cationic multifunctional liposome-mediated delivery of COX-2 siRNA.' "Liposomes are a useful means of delivering molecular targeting agents such as small interfering RNA (siRNA) to downregulate specific pathways important in cancer growth and progression. The ability to non-invasively image these carriers is important to ascertain their delivery within the tumor," scientists in the United States report.

"As cyclooxygenase-2 (COX-2) is an important therapeutic target in cancer, we investigated loading COX-2-specific siRNA into cationic liposomes containing MR contrast agents for imaging delivery in cancer cells and...

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