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Cancer Weekly

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Cancer Gene Therapy



Data on cancer gene therapy detailed by researchers at University of Texas, M.D. Anderson Cancer Center



February 24th, 2009

New research, 'Oncolytic adenovirus retargeted to Delta-EGFR induces selective antiglioma activity,' is the subject of a report. According to recent research from the United States, "The fact that glioblastomas, which are one of the most devastating cancers, frequently express the Delta-EGFR (epithelial growth factor receptor) also called mutant variant III of EGFR (EGFRvIII) suggests that this cancer cell-specific receptor might serve as an ideal target for cancer therapy. To assess its potential as such a target, we constructed an oncolytic adenovirus with Retargeted Infectivity Via EGFR (Delta-24-RIVER) on the backbone of Delta-24."

"This new oncolytic adenovirus...


Source: Cancer Weekly (2009-02-24)

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