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Cancer Gene Therapy
Data on cancer gene therapy discussed by researchers at Osaka University
February 24th, 2009
A report, 'The effects of trichostatin A on the oncolytic ability of herpes simplex virus for oral squamous cell carcinoma cells,' is newly published data in Cancer Gene Therapy. According to a study from Suita, Japan, "Combining the use of a chemotherapeutic agent with oncolytic virotherapy is a useful way to increase the efficiency of the treatment of cancer. The effect of the histone diacetylase (HDAC) inhibitor trichostatin A (TSA) on the antitumor activity of a herpes simplex virus type-1 (HSV-1) mutant was examined in oral squamous cell carcinoma (SCC) cells." "Immunoblotting analysis and immunoflourescence staining revealed that a cytoplasmic nuclear...
Source: Cancer Weekly (2009-02-24)
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