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Cancer Weekly

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Cancer Gene Therapy



Data on cancer gene therapy reported by researchers at Peking Union Medical College



February 24th, 2009

Fresh data on cancer gene therapy are presented in the report 'Combined silencing of K-ras and Akt2 oncogenes achieves synergistic effects in inhibiting pancreatic cancer cell growth in vitro and in vivo.' "Cancer is a complex disease involving multiple oncogenes with diverse actions. Inhibiting only one oncogene is unlikely to eliminate the malignancy of cancer cells," researchers in Beijing, People's Republic of China report.

"The goal of this study was to investigate whether synergistic effects can be achieved by combined silencing of two oncogenes, K-ras and Akt2, which are key players in the Ras/MAPK and PI3K/Akt signaling pathways. The pancreatic cancer cell line,...


Source: Cancer Weekly (2009-02-24)

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