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Cancer Weekly

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Cancer Gene Therapy



Investigators at Sun Yat-Sen University, Cancer Center publish new data on cancer gene therapy



February 24th, 2009

Scientists discuss in 'The pivotal role of c-Jun NH2-terminal kinase-mediated Beclin 1 expression during anticancer agents-induced autophagy in cancer cells' new findings in cancer gene therapy. According to a study from Guangzhou, People's Republic of China, "The c-Jun NH2-terminal kinase (JNK) pathway represents one subgroup of MAP kinases that are activated primarily by cytokines and exposure to environmental stress. Autophagy is a protein-degradation system characterized by the formation of double-membrane vacuoles termed autophagosomes."

"Autophagy-related gene beclin 1 plays a key role in autophagosome formation. However, the relationships between activation of...


Source: Cancer Weekly (2009-02-24)

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