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Cancer Weekly

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Cancer Gene Therapy



Recent studies by A.W. Tong and co-authors add new data to cancer gene therapy findings



February 24th, 2009

Research findings, 'MicroRNA profile analysis of human prostate cancers,' are discussed in a new report. "We examined the microRNA (miRNA) expression profile of 40 prostatectomy specimens from stage T2a/b, early relapse and non-relapse cancer patients, to better understand the relationship between miRNA dysregulation and prostate oncogenesis. Paired analysis was carried out with microdissected, malignant and non-involved areas of each specimen, using high-throughput liquid-phase hybridization (mirMASA) reactions and 114 miRNA probes," investigators in the United States report.

"Five miRNAs (miR-23b, -100, -145, -221 and -222) were significantly downregulated in...


Source: Cancer Weekly (2009-02-24)

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