Colon Cancer

Research from Medical University of Graz in the area of colon cancer published

Published in Cancer Weekly, February 24th, 2009

"Integrins such as alpha(2)beta(1), alpha(IIb)beta(3), and alpha(v)beta(3) have been suggested as key players for cancer development and progression. Several polymorphisms affecting these molecules, two in integrin alpha(2) (ITGA2 807C > T and 1648G > A) and one in beta(3) (ITGB3 176T > C), influence their levels, structure, and possibly their function," scientists in Graz, Austria report.

"To analyze the role of ITGA2 and ITGB3 polymorphisms for colorectal cancer risk and clinical presentation, we performed a case-control study. Four hundred thirty-three colorectal cancer patients and 433 healthy sex- and age-matched control subjects were investigated. ITGA2...

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Source: Cancer Weekly (2009-02-24)

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