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Cancer Gene Therapy
Researchers from Justus-Liebig University, Department of Internal Medicine II publish findings in cancer gene therapy
February 24th, 2009
Scientists discuss in 'Intravenous injection of siRNA directed against hypoxia-inducible factors prolongs survival in a Lewis lung carcinoma cancer model' new findings in cancer gene therapy. According to recent research from Giessen, Germany, "Different routes for the in vivo administration of synthetic siRNA complexes targeting lung tumors were compared, and siRNA complexes were administered for the inhibition of hypoxia-inducible factor (HIF-1alpha and HIF-2alpha). Intravenous jugular vein injection of siRNA proved to be the most effective means of targeting lung tumor tissue in the Lewis lung carcinoma (LLC1) model." "In comparison, intraperitoneal injection of...
Source: Cancer Weekly (2009-02-24)
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