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Enzyme Research
Reports summarize enzyme research from Kyungpook National University, College of Natural Sciences
February 24th, 2009
A report, 'Silencing of cytosolic NADP(+)-dependent isocitrate dehydrogenase by small interfering RNA enhances the sensitivity of HeLa cells toward staurosporine,' is newly published data in Free Radical Research. According to recent research published in the journal Free Radical Research, "Staurosporine induces the production of reactive oxygen species, which play an important causative role in apoptotic cell death. Recently, it was demonstrated that the control of cellular redox balance and the defense against oxidative damage is one of the primary functions of cytosolic NADP(+)-dependent isocitrate dehydrogenase (IDPc) by supplying NADPH for antioxidant systems."...
Source: Cancer Weekly (2009-02-24)
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