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Gene Therapy
Scientists at New York University, University Cancer Institute report research in gene therapy
February 24th, 2009
A new study, 'Controlled propagation of replication-competent Sindbis viral vector using suicide gene strategy,' is now available. "A major concern of using viral gene therapy is the potential for uncontrolled vector propagation and infection that might result in serious deleterious effects. To enhance the safety, several viral vectors, including vectors based on Sindbis virus, were engineered to lose their capability to replicate and spread after transduction of target cells," scientists in the United States report. "Such designs, however, could dramatically reduce the therapeutic potency of the viral vectors, resulting in the need for multiple dosages to achieve...
Source: Cancer Weekly (2009-02-24)
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