Cancer Weekly
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Adenocarcinoma
New adenocarcinoma research from R.S. Saad et al outlined
February 24th, 2009
"We studied tumor lymphatic vascular density (L VD) as a predictive marker for the risk of lymph node (LN) metastasis and its relationship to other prognostic parameters and survival in 75 patients with esophageal adenocarcinoma. Samples were immunostained for D2-40, CD31, and vascular endothelial growth factor (VEGF)," scientists in Toronto, Canada report. "Microvessels were counted in densely vascular/lymphatic foci (hot spots) at x 400 field (0.17 mm(2)). Intensity of staining for VEGF was scored on a 2-tiered scale. CD31 microvessel counts showed significant correlation with tumor stage and patient survival (P < .01). D2-40 LVD demonstrated a significant...
Source: Cancer Weekly (2009-02-24)
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