Cancer Weekly
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Adenocarcinoma
Studies from Vanderbilt University yield new information about adenocarcinoma
February 24th, 2009
According to a study from the United States, "Expression of transcription factors that mediate epithelial-mesenchymal transition (EMT), such as Twist and Slug, is correlated with poor prognosis in many tumor types. Selected EMT markers were studied in a series of pancreatic ductal adenocarcinomas (PDAs) and benign pancreatic tissues to determine whether expression levels correlated with diagnosis, histologic grade, or patient outcome." "Immunohistochemical stains for Twist, Slug, and N-cadherin were performed using a tissue microarray containing 68 PDAs and 38 samples of normal pancreas or chronic pancreatitis tissues. Twist and Slug were identified in both the nucleus...
Source: Cancer Weekly (2009-02-24)
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