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Cancer Weekly

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Antibiotics



New antibiotics study findings have been published by R. Fiskesund and colleagues



February 24th, 2009

"To prepare 1,5-anhydro-d-fructose (AF) derivatives, test their microbial inhibition spectrum, and to further examine the most effective AF derivative against Pseudomonas aeruginosa and malignant blood cell lines. Microthecin and nine other AF derivatives were synthesized from AF," scientists writing in the Journal of Applied Microbiology report.

"The 10 compounds were tested in vitro against Gram-positive (GP) and Gram-negative (GN) bacteria, yeasts and moulds using a well diffusion method and in a Bioscreen growth analyser. Of the test compounds, microthecin exhibited the most significant antibacterial activity at 100-2000 ppm against both GP and GN bacteria,...


Source: Cancer Weekly (2009-02-24)

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