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Cancer Gene Therapy
Studies in the area of cancer gene therapy reported from University of Tsukuba
March 3rd, 2009
According to recent research published in the journal Cancer Gene Therapy, "Combination therapy with replicative oncolytic viruses is a recent topic in innovative cancer therapy, but few studies have examined the efficacy of oncolytic adenovirus plus replication-deficient adenovirus carrying a suicide gene. We aim to evaluate whether an E1A, E1B double-restricted oncolytic adenovirus, AxdAdB-3, can improve the efficacy for gallbladder cancers (GBCs) of the replication-deficient adenovirus-based herpes simplex virus thymidine kinase (HSVtk)/ganciclovir (GCV) therapy directed by the carcinoembryonic antigen (CEA) promoter." "Cytopathic effects of AxdAdB-3 plus...
Source: Cancer Weekly (2009-03-03)
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