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Duke University Medical Center
Newly discovered gene could be a prime target in the most lethal brain cancer
March 3rd, 2009
Scientists at Duke University Medical Center and Johns Hopkins University have discovered mutations in two genes that could become therapeutic targets in malignant glioma, a dangerous class of brain tumors. "The fact that the defective genes code for metabolic enzymes found only in malignant glioma, and not in normal tissue, could make the gene products therapeutic targets," says Hai Yan, M.D., Ph.D., lead author, an assistant professor in the Duke Department of Pathology. The findings are published in the Feb. 19 issue of the New England Journal of Medicine. These genetic flaws might also help distinguish between primary and secondary glioblastoma...
Source: Cancer Weekly (2009-03-03)
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