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Cancer Gene Therapy
Jinan University details research in cancer gene therapy
March 3rd, 2009
A report, 'Somatostatin analogues inhibit cancer cell proliferation in an SSTR2-dependent manner via both cytostatic and cytotoxic pathways,' is newly published data in Oncology Reports. "Somatostatin receptors (SSTRs) are inhibitory G-protein coupled receptors that are ubiquitously expressed in normal and cancer cells. Somatostatins (SST) are the natural ligands for SSTRs and act as inhibitory regulators of hormone secretion and proliferation," researchers in Guangzhou, People's Republic of China report. "Octreotide and RC-160 (vapreotide) are two well tolerated SSTR2/SSTR5 selective somatostatin analogues (SSA) that have been used in the treatment of cancers...
Source: Cancer Weekly (2009-03-03)
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