Cancer Weekly
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Adenoma
New adenoma data have been reported by A.K. Gupta and co-authors
March 3rd, 2009
According to recent research from the United States, "Purpose of review There is a wealth of literature, both from epidemiological and molecular studies, which support the role of aberrant crypt foci (ACF) as a putative precursor to colorectal adenomas and a potential biomarker for colorectal carcinoma. In this review, we critically examine the evidence on employing ACF as an intermediate endpoint." "Recent findings Recent, larger-scale, multicenter studies of ACF have raised questions about ACF. The prevalence of ACF has not correlated with colorectal adenomas, and the technique for ACF detection using high-magnification chromoendoscopy has demonstrated considerable...
Source: Cancer Weekly (2009-03-03)
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