Cancer Weekly
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Angiogenesis
New angiogenesis study findings have been reported from Southampton General Hospital
March 3rd, 2009
" We have observed cavitation of lesions in clinical trials of an angiogenesis inhibitor combined with chemotherapy for non-small-cell lung cancer (NSCLC). We hypothesized that cavitation might alter response assessment in such clinical trials," scientists in Southampton, the United Kingdom report. "Patients and Methods We performed a retrospective radiologic review of patients with NSCLC enrolled onto three National Cancer Institute of Canada Clinical Trials Group (NCIC CTG) trials of platinum-based chemotherapy with or without a small-molecule angiogenesis inhibitor (vascular endothelial growth factor receptor inhibitor [VEGFRI]). Response was assessed both by...
Source: Cancer Weekly (2009-03-03)
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