Cancer Weekly
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Aplastic Anemia
New aplastic anemia research reported from Kanazawa University
March 3rd, 2009
"Moesin is an intracellular protein that links the cell membrane and cytoskeleton, while also mediating the formation of microtubules and cell adhesion sites as well as ruffling of the cell membrane. To determine the roles of anti-moesin Abs derived from the serum of patients with aplastic anemia (AA) in the pathophysiology of bone marrow failure, we studied the expression of moesin on various blood cells and the effects of anti-moesin Abs on the moesin-expressing cells," investigators in Kanazawa, Japan report. "The proteins recognized by anti-moesin mAbs were detectable on the surface of T cells, NK cells, and monocytes from healthy individuals as well as on THP-1...
Source: Cancer Weekly (2009-03-03)
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