Cancer Weekly
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Cancer Vaccines
Research from University of Cologne reveals new findings on cancer vaccines
March 10th, 2009
"Cellular adjuvants such as dendritic cells (DC) are in the focus of tumour immunotherapy. In DC-vaccine trials, induction of tumour antigen-specific immunity is observed frequently and well-documented clinical responses have been reported," researchers in Cologne, Germany report. "However, the overall response rate is less than 3%, therefore alternative strategies are being investigated. CD40-activated B cells (CD40-B) have been characterized previously as an interesting alternative because they present antigen efficiently and can be expanded by several logs from small amounts of peripheral blood. To determine the central technical challenges of cell-based vaccines we...
Source: Cancer Weekly (2009-03-10)
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