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Cancer Gene Therapy
Study findings from Scripps Research Institute provide new insights into cancer gene therapy
March 10th, 2009
Scientists discuss in 'Deficiency of a potential 3p21.3 tumor suppressor gene UBE1L (UBA7) does not accelerate lung cancer development in K-rasLA2 mice' new findings in cancer gene therapy. "Genetic lesions in chromosomal region 3p21.3 marks one of the earliest events in human lung cancer development. It is hypothesized that one or more tumor suppressor genes reside in this region," researchers in the United States report. "Identification and characterization of these genes are important for the understanding of lung cancer initiation. UBE1L (UBA7) is a long-suspected 3p21.3 residing tumor suppressor gene. It encodes the key enzyme that activates ISGylation, a novel,...
Source: Cancer Weekly (2009-03-10)
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