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Cancer Weekly

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Acromegaly



Research on acromegaly reported by F. Castinetti et al



March 10th, 2009

According to recent research published in the journal Pituitary, "Growth-hormone hypersecretion, acromegaly, is associated with reduced life expectancy. First line treatment remains surgery, but remission rates vary between 50% and 90%."

"In case of lack of surgical remission or recurrence, somatostatin agonists can be proposed. However, about 30% of patients are partially or totally resistant to this treatment. The growth hormone receptor antagonist pegvisomant currently needs more prolonged follow-up studies. Conventional radiotherapy and radiosurgery are two radiation treatment modalities that can be proposed to these resistant patients. Reported rates of...


Source: Cancer Weekly (2009-03-10)

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