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Cancer Weekly

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Apoptosis



Research reports on apoptosis from D.P. Santana and colleagues provide new insights



March 10th, 2009

According to recent research from Sao Paulo, Brazil, "Permeabilization of the mitochondrial membrane has been extensively associated with necrotic and apoptotic cell death. Similarly to what had been previously observed for B16F10-Nex2 murine melanoma cells."

"PdC (palladacycle compounds) obtained from the reaction of dmpa (N,N-dimethyl-1-phenethylamine) with the dppe [1,2-ethanebis(diphenylphosphine)] were able to induce apoptosis in HTC (hepatoma, tissue culture) cells, presenting anticancer activity in vitro. To elucidate cell site-specific actions of dmpa:dppe that. could respond to the induction of apoptosis in cancer cells in the present Study, we investigated the...


Source: Cancer Weekly (2009-03-10)

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