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Thyroid Cancer Cell Biology

Sao Paulo Federal University, Division of Genetics publishes research in thyroid cancer cell biology

Published in Cancer Weekly, March 10th, 2009

A new study, 'Down-regulation of NR4A1 in follicular thyroid carcinomas is restored following lithium treatment,' is now available. According to a study from Sao Paulo, Brazil, "The identification of follicular thyroid adenoma-associated transcripts will lead to a better understanding of the events involved in pathogenesis and progression of follicular tumours. Using Serial Analysis of Gene Expression, we identified five genes that are absent in a malignant follicular thyroid carcinoma (FTC) library, but expressed in follicular adenoma (FTA) and normal thyroid libraries."

"NR4A1, one of the five genes, was validated in a set of 27 normal thyroid tissues, 10 FTAs and 14...

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