Cancer Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Cancer Vaccines Therapy
Researchers from University of Pittsburgh, Department of Pathology describe findings in cancer vaccines therapy
March 17th, 2009
Current study results from the report, 'Interferon regulatory factor 8 mediates tumor-induced inhibition of antigen processing and presentation by dendritic cells,' have been published. "Suppression of dendritic cells (DCs) is a crucial mechanism by which tumor cells escape immune recognition and elimination. We have recently reported that MHC class I antigen processing machinery (APM) component expression in human DCs is down-regulated by tumor-derived gangliosides," scientists writing in the journal Cancer Immunology, Immunotherapy report. "However, the molecular mechanisms underlying this abnormality were not identified. Thus, the aim of this work was to...
Source: Cancer Weekly (2009-03-17)
|
