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Cancer Weekly

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Immunization



Researchers from National Institutes of Health publish findings in immunization



March 17th, 2009

Scientists discuss in 'Antigen-presenting cells containing multiple costimulatory molecules promote activation and expansion of human antigen-specific memory CD8+ T cells' new findings in immunization. According to recent research from the United States, "We have previously demonstrated that multiple immunizations with vector-based vaccines containing transgenes for tumor Ags and a triad of costimulatory molecules (TRICOM) enhance the expansion and functional avidity of Ag-specific memory CD8(+) T cells in a mouse model. However, the effect of enhanced costimulation on human memory CD8(+) T cells is still unclear."

"The study reported here was an in vitro investigation...


Source: Cancer Weekly (2009-03-17)

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