Cancer Weekly
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Adenocarcinoma
Research from L. Badea et al broadens understanding of adenocarcinoma
March 17th, 2009
According to recent research from Bucharest, Romania, "The precise details of pancreatic ductal adenocarcinoma (PDAC) pathogenesis are still insufficiently known, requiring the use of hig-throughput methods. However, PDAC is especially difficult to study using microarrays due to its strong desmoplastic reaction, which involves a hyper-proliferating stroma that effectively ''masks'' the contribution of the minoritary neoplastic epithelial cells." "Thus it is not clear which of the genes that have been found differentially expressed between normal and whole tumor tissues are due to the tumor epithelia and which simply reflect the differences in cellular composition. To...
Source: Cancer Weekly (2009-03-17)
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