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Cancer Weekly

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Angiogenesis



New angiogenesis findings from J. Ming and co-authors described



March 17th, 2009

According to recent research from Shenyang, People's Republic of China, "The aim of this study was to investigate the mechanism of PRL-3 in inducing angiogenesis and lymphangiogenesis to promote distant and lymph node metastasis in human lung cancer tissues and cells. We investigated the expression of PRL-3, VEGF, and VEGF-C from 94 patients with non-small cell lung cancer (NSCLC) using immunohistochemical staining."

"The relationship between PRL-3 expression and microvessel density (MVD), lymphatic vessel density (LVD), clinicopathological factors, and surgical treatment outcome was also studied. Following this, we studied the effect on A549 by blocking PRL-3. PRL-3...


Source: Cancer Weekly (2009-03-17)

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