Cancer Weekly
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Angiogenesis
Studies from University of Hong Kong yield new information about angiogenesis
March 17th, 2009
According to recent research published in the International Journal of Colorectal Disease, "We observed a marked synergism between peroxisome proliferator-activated receptor gamma (PPAR gamma) ligands and X-linked inhibitor of apoptosis (XIAP) down-regulation in colon cancer. In the current study, we detected the gene expression profile in HCT116 cells treated with or without PPAR gamma ligand troglitazone." "HCT116-XIAP(+/+) and HCT116-XIAP(-/-) cells were treated with or without 50 mc M troglitazone for 48 h. Gene expressions were detected by microarray, and selected genes were validated by reverse-transcriptase polymerase chain reaction (PCR), real-time PCR,...
Source: Cancer Weekly (2009-03-17)
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