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Angiogenesis

Researchers from Research Center describe findings in angiogenesis

Published in Cancer Weekly, March 17th, 2009

Research findings, 'Genetics, epigenetics and pharmaco-(epi)genomics in angiogenesis,' are discussed in a new report. According to a study from Leuven, Belgium, "Angiogenesis is controlled by a balance between pro-and anti-angiogenic factors. Studies in mice and human beings have shown that this balance, as well as the general sensitivity of the endothelium to these factors, is genetically pre-determined."

"In an effort to dissect this genetic basis, different types of genetic variability have emerged: mutations and translocations in angiogenic factors have been linked to several vascular malformations and haemangiomas, whereas SNPs have been associated with complex...

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