Cancer Weekly
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B-Cell Lymphoma
New B-cell lymphoma findings from J.J. Oudejans and co-researchers published
March 17th, 2009
"Diffuse large B-cell lymphomas (DLBCL) are highly heterogeneous with regard to clinical presentation and outcome. DLBCL copy number aberrations have been identified previously, of which the deletion at 6q21-24 was significantly associated with a highly favorable clinical response to chemotherapy," scientists in Netherlands report. "In this study, we aimed to identify genes implicated in this and other genomic regions with recurrent losses and/or gains. To identify implicated genes, we superimposed array comparative genomic hybridization (aCGH) data onto a microarray expression dataset of 42 clinically well-characterized primary nodal DLBCL biopsies. We confirmed that...
Source: Cancer Weekly (2009-03-17)
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