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Cancer Weekly

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Acute Myeloid Leukemia



Study data from M. Gross and co-authors update knowledge of acute myeloid leukemia



March 24th, 2009

"Acute myeloid leukemia (AML) is a heterogeneous disease with respect to clinical Prognosis and acquired chromosomal aberrations. After routine banding cytogenetic analysis 45% of AML patients snow a normal karyotype (NK-AML)," scientists in Jena, Germany report.

"For a better understanding of development and progression in AML, it is important to find markers which could be primary genetic aberrations. Therefore, in this study 31 patients with NK-AML were analyzed by new high resolution molecular cytogenetic approaches. A combination Of Multitude multicolor banding and metaphase microdissection-based comparative genomic hybridization revealed deletions of the...


Source: Cancer Weekly (2009-03-24)

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