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Antisense Technology
Study results from Sullivan University update understanding of antisense technology
March 24th, 2009
"microRNAs (miRNAs) are post-transcriptional regulators of gene expression that play a role in viral infection. We have developed a method to identify viral-encoded miRNAs from viruses in which abundant amounts of infected material is limiting," scientists in the United States report. "We show that Merkel Cell Polyomavirus (MCV), a recently identified human virus associated with cancer, encodes a miRNA. This miRNA is expressed from the late strand, lies antisense to the early transcripts and negatively regulates expression of chimeric reporters containing a portion of the early transcripts," wrote G.J. Seo and colleagues, Sullivan University. The...
Source: Cancer Weekly (2009-03-24)
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