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Apoptosis
Findings from Hong Kong Baptist University provide new insights into apoptosis
March 24th, 2009
According to recent research from Hong Kong, People's Republic of China, "Astragalus membranaceus has been used to ameliorate the side effects of anti-neoplastic drugs. We recently reported that total Astragalus saponins (AST) possess antitumor properties in human colon cancer cells and tumor xenografts." "Nevertheless, the precise mechanism of action has not been fully elucidated. The present study aimed to unveil the anti-carcinogenic potential of AST in HepG2 human hepatocellular carcinoma (HCC) cells and to clarify the signaling pathway. We demonstrated here that AST downregulated expression of the HCC tumor marker alpha-fetoprotein and Suppressed HepG2 cell growth...
Source: Cancer Weekly (2009-03-24)
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