Colon Cancer Genetics
New colon cancer genetics data have been reported by S. Asaka and co-authors
Published in Cancer Weekly, March 24th, 2009
Scientists discuss in 'Microsatellite instability-low colorectal cancer acquires a KRAS mutation during the progression from Dukes' A to Dukes' B' new findings in colon cancer. "The classification of colorectal cancer (CRC) by microsatellite instability (MSI) status is important for effective clinical management. In fact, microsatellite instability-high (MSI-H) cancer has distinctive clinicopathological and molecular features," researchers in Saitama, Japan report.
"However, microsatellite instability-low (MSI-L) cancer is not clearly defined. The objective of this study was to further clarify the characteristics of MSI-L CRC. A consecutive series of 940 primary CRCs...
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Source: Cancer Weekly (2009-03-24)
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