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Cancer Gene Therapy
New findings in cancer gene therapy described from Memorial Sloan Kettering Cancer Center
March 31st, 2009
New investigation results, 'Simultaneous haploinsufficiency of Pten and Trp53 tumor suppressor genes accelerates tumorigenesis in a mouse model of prostate cancer,' are detailed in a study published in Differentiation. "Tumor suppressor gene PTEN is important in the initiation and progression of human prostate carcinoma, whereas the role of TP53 remains controversial. Since Pten/Trp53 double conditional knockout mice show earlier onset and fast progression of prostate cancer when compared to Pten knockout mice, we asked whether heterozygosity of these two tumor suppressor genes was sufficient to accelerate prostatic tumorigenesis," investigators in the United States report....
Source: Cancer Weekly (2009-03-31)
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