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Cancer Gene Therapy
Research reports on cancer gene therapy from Institute of Cancer Research provide new insights
March 31st, 2009
Researchers detail in 'Targeting Tankyrase 1 as a therapeutic strategy for BRCA-associated cancer,' new data in cancer gene therapy. According to a study from London, the United Kingdom, "The BRCA1 and BRCA2 proteins are involved in the maintenance of genome stability and germ-line loss-of-function mutations in either BRCA1 or BRCA2 strongly predispose carriers to cancers of the breast and other organs. It has been demonstrated previously that inhibiting elements of the cellular DNA maintenance pathways represents a novel therapeutic approach to treating tumors in these individuals." "Here, we show that inhibition of the telomere-associated protein, Tankyrase 1, is also...
Source: Cancer Weekly (2009-03-31)
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