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Cancer Weekly

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Cancer Gene Therapy



Researchers from INSERM discuss findings in cancer gene therapy



March 31st, 2009

New investigation results, 'Preclinical study of an ex vivo gene therapy protocol for hepatocarcinoma,' are detailed in a study published in Cancer Gene Therapy. "Preclinical studies in several animal models as well as clinical trials have shown a reduction in tumor growth following immunotherapy with interleukin-12 (IL-12). This cytokine is appropriate to test in therapeutic clinical trials to treat hepatocarcinoma (HC), a pathology often associated with hepatitis B or C-induced cirrhosis," investigators in Toulouse, France report.

"The local delivery into the liver would be achieved through ex vivo gene transfer using retroviral (rv) vectors in autologous...


Source: Cancer Weekly (2009-03-31)

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