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Cancer Gene Therapy
Researchers from Jinan University describe findings in cancer gene therapy
March 31st, 2009
Current study results from the report, 'Overexpression of SSTR2 inhibited the growth of SSTR2-positive tumors via multiple signaling pathways,' have been published. "Somatostatin receptors (SSTR1-5) are inhibitory G-protein coupled receptors that are ubiquitously expressed in both normal and cancer cells. Activation of SSTRs results in inhibition of hormone secretion and cell proliferation," scientists writing in the journal Acta Oncologica report. "Loss-of-expression of SSTR2 in tumor tissues has been suggested to correlate with tumor progression and to the relatively poorer outcomes of somatostatin analog treatment in some clinical trials. Therefore, gene...
Source: Cancer Weekly (2009-03-31)
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