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Gene Therapy
Tianjin Medical University, Department of Neurosurgery details research in gene therapy
March 31st, 2009
A report, 'Downregulation of Wnt2 and beta-catenin by siRNA suppresses malignant glioma cell growth,' is newly published data in Cancer Gene Therapy. "Increasing evidence suggests that aberrant activation of Wnt signaling is involved in tumor development and progression. Our earlier study on gene expression profile in human gliomas by microarray found that some members of Wnt family were overexpressed," researchers in Tianjin, People's Republic of China report. "To further investigate the involvement of Wnt signaling in gliomas, the expression of core components of Wnt signaling cascade in 45 astrocytic glioma specimens with different tumor grades was examined by...
Source: Cancer Weekly (2009-03-31)
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